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pentobarbital will minimize the extent or impact of pazopanib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.pentobarbital will lower the extent or effect of celecoxib by impacting hepatic enzyme CYP2C9/10 metabolism. Insignificant/Importance Not known.pentobarbital will decrease the level or effect of glecapre